How to pronounce“adeno”in English

adenoids um this is very important a narrow nasal passage so this can be due

Adenosine monophosphate. That is one of the sub-unit monomers of all nucleic acids.

adenosine receptors no surprise there and it creates the feeling of sleepiness

adenosine or time of day the circadian thing we were talking about earlier an additional factor is that effort is in related to the

And adenosine is like a marker of sleep deprivation.

And it poops out adenosine.

And that's why adenosine is a very good marker for sleepiness across the day.

of a chemical called adenosine.

site specifically for adenosine.

We want adenosine to raise at a very consistent level, get to a certain point.

in the case of adenovirus the years and years of people studying it has told us what genes you could cut out and allow the virus to infect the cell

get sleepy as adenosine accumulates the longer we've been awake the more adenosine is accumulated in our system

rhinovirus an adenovirus or is it flu and you know we can do that we can start building the rules of virus spread across the

Capsids are the protein shells of adeno-associated virus.

What caffeine is doing is actually blocking adenosine from hitting your receptors.

because it's all that adenosine and that's actually now made its way through the floodgates.

at particular times irrespective of adenosine.

That's a situation where your adenosine is very, very high, but your circadian rhythm is off, because you went to bed too early.

You'll reduce the amount of adenosine in your system so that you're not as sleepy.

Many of you know ATP to be adenosine triphosphate, the energy carrying shuttle service molecule found

vaccines the MRNA vaccines and the adenovector DNA vaccine all share the same vulnerability which is they are very narrowly focused on one subunit of

AAVs, adeno-associated virus, is a parasite of other viruses.

And caffeine basically muscles in and masks the adenosine receptors.

And the feedback from the doctor was her adenoids are a little enlarged, but he kind of said it's up to you

And I would also want to know related to her adenoids, breathing, all that kind of stuff, she may be waking because she's actually thirsty

Part of what comes out the back end is adenosine, and adenosine works its way through the bloodstream, gets into the brain, and it goes to a very specific receptor

Now, adenosine is the thing that your brain produces throughout the day-- which is what makes you sleepy-- and is the thing that cues you to go

vaccines are vectors of different kinds of most famous or adenovirus vectors carrying the spike gene into the cell can you explain how the

now it turns out that those are called adenosine receptors and maybe we can speak about what adenosine is and sleep pressure and all of that good stuff but

but how sleepy we get for a given amount of adenosine depends on where we are in this so-called circadian cycle

you could say well provided i sleep and push adenosine back downhill which is what happens when we sleep adenosine is then reduced and provided i am on

Because when you combine the two, the adenosine and the insulin receptors in the brain now become more frazzled, and you can't focus.

But when the caffeine degrades, the adenosine is still there.

he may outgrow. Tonsils and adenoids tend to grow exponentially large in children between the ages of 2 and 5.

Now, does anybody in this room use an adenosine blocker for their health?

OK. So caffeine is an adenosine blocker, and the reason why caffeine works in waking you up is because its effect on adenosine.

and those are the set of vaccine vectors that we're using so it includes adenovirus vesicular stomatitis virus which is a

that's super important which is that the longer we are awake the more adenosine accumulates in our brain and adenosine binds to

my normal wake-up time i'll start to feel more alert even though adenosine has been accumulating further so adenosine is higher for me

And as you use your energy, you have these little adenosine molecules that actually get built up along with that energy use.

And it's telling you that you're not-- that you don't have that much adenosine in your system.

And so you can get this wave of tiredness, this caffeine crash from all the adenosine that's been building up.

That make sense? If someone has a cold or a flu and their tonsils and adenoids are inflamed, there's going to be a change as well.

We took her to an ENT when she was much younger to see if she had an adenoid issue or some other breathing issue.

Well, it turns out that if you look at the molecular structure of adenosine, and you look at the molecular structure of caffeine, they're off by one molecule.

and it fits really nicely into that receptor site, and it blocks the adenosine.

But then once your brain burns through the caffeine, the adenosine comes flooding in, and that's where you get that caffeine crash,

that's number one um and I break down the book how caffeine actually works with adenosine and all that stuff and

They should be banned for being horrible, unnecessary, and adenoidally grating.