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They've succeeded in restoring plasticity to the visual cortex in order to permit reconnection between the eye and the brain, reconnections that would not ever occur otherwise.
These downregulating systems are now drug targets.
And the hunt is on to design or find drugs that will release the central nervous system from the inhibition of innate plasticity and repair
Listen to native speakers pronounce “downregulating” in real conversational contexts with synchronized timestamps and subtitles.