How to pronounce“haloalkane”in English

For example, mixing a haloalkane with sodium hydroxide will cause the hydroxyl group to displace the halide ion.

They can be made in a similar way to Grignard reagents: you add a haloalkane to two molar equivalents of lithium metal, using ether as a solvent.

To make an amine, the simplest nucleophilic substitution is reacting ammonia with a haloalkane.

Like the azide reaction, the first step is nucleophilic substitution with a haloalkane.

First, we need to make a phosphonium salt by reacting triphenylphosphine with a haloalkane in an SN2 reaction -- head back to episodes 20 and 21 for a refresher on these concepts.

In theory, we can make all sorts of things – like haloalkanes!

Now, plain old organocopper reagents, which have one copper-carbon bond, can’t easily be made by mixing copper metal and a haloalkane in a solvent, because copper is much more difficult to oxidize.