How to pronounce“crosslink”in English
verbThe active site is blocked by the large penicillin structure… and that’s it! Nothing else can happen.
The transpeptidase can't crosslink any more cell walls, which weakens them and leaves the bacteria unprotected from its environment. So it bursts and dies. Bye-bye bacteria.
An irreversible inhibitor binds to an enzyme active site, permanently deactivating it. This is what penicillin does to the transpeptidase enzyme -- by forming a covalent bond.
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Definitions of “crosslink”
Alternative spelling of cross-link.
Alternative spelling of cross-link.
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