How to pronounce“retrosynthesis”in English
Like we learned in Episode 34, using retrosynthesis to figure out how to make something is a lot of what we do in organic chemistry.
Retrosynthesis is a bit like cutting up a beautiful cake to figure out the decorations, filling, and ingredients so you can make the same cake yourself from scratch.
Just… don’t try to taste your reactions… So, for example, here's a cool compound: we notice this structure contains an enone, where an alkene is conjugated with a carbonyl,
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Definitions of “retrosynthesis”
The prediction of precursors (intermediates and reactants), given the products of a synthesis reaction.
“1983, Francis A. Carey, Richard J. Sundberg, Advanced Organic Chemistry: Reactions and synthesis, Plenum Press, page 578, The retrosyntheses shown in Scheme 11.11 correspond to the syntheses in Schemes 11.12 and 11.13.”
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