How to pronounce“chromosomeful”in English
This gave scientists a pretty big clue that maybe it was the “dosage” of chromosome X that was responsible for the increased susceptibility to autoimmune disorders.
Dosage is an odd choice of words in this case, but it just refers to how much output you’re getting from any given gene, or “chromosomeful” of genes, as it were.
To understand why this matters, you only need to know that duplications of most autosomes are fatal, with the only real exception being three copies of number 21.
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