How to pronounce "synthetases" in English
SYN·the·ta·ses
Primary stress: syn
Hear native speakers say synthetases in context across real video clips
today is with a review of tRNAs and then discussing the aminoacyl-tRNA synthetases, which are the enzymes responsible for loading amino acids onto the three prime end of the tRNA. are the enzymes responsible for loading
Linguistic Pronunciation Masterclass: “synthetases”
Phonetic mechanics, syllable architecture, and conversational cadence
Syllable Architecture & Stress Distribution
SYN
Elevated pitch, sustained vowel length, and full acoustic clarity.
the
Reduced vowel sound, relaxed jaw, and minimal vocal effort.
ta
Reduced vowel sound, relaxed jaw, and minimal vocal effort.
ses
Reduced vowel sound, relaxed jaw, and minimal vocal effort.
Primary emphasis falls on the first syllable ("SYN"). Raise your pitch and sustain the vowel length on this syllable while relaxing the surrounding syllables.
Common Pronunciation Traps & Learner Mistakes
The Trap: Many learners substitute "th" with "s", "z", "t", or "d".
How Native Speakers Say It: Place the flat blade of your tongue lightly between your upper and lower incisors. Vibrate your vocal cords while pushing air through to produce ⁄ð⁄.
The Trap: Pronouncing a hard, aspirated [tʰ] in casual conversation can sound overly formal in North America.
How Native Speakers Say It: In American English, a single "t" between vowels quickly taps against the alveolar ridge like a soft "d" ([ɾ]). In British English, maintain a crisp aspirated [tʰ].
Connected Speech & Natural Conversational Flow
When "synthetases" is followed by a word starting with a vowel, glide the final consonant into the opening vowel (e.g. "synthetases is" sounds like "synthetases-iz").
Maintain the stress-timed rhythm of English: compress unstressed syllables rapidly so the beat of "synthetases" aligns naturally with adjacent words.
Authentic Spoken Quotes from Native Video Context
“the aminoacyl-tRNA synthetases, which are the enzymes responsible for loading amino acids onto the three prime end of the tRNA.”— MIT OpenCourseWareWatch clip
“And in order for that to happen, there's a family of enzymes called aminoacyl-tRNA synthetases, or abbreviated aaRS.”— MIT OpenCourseWareWatch clip
“So in the case of these aminoacyl-tRNA synthetases, these ATP PPI exchange assays work well.”— MIT OpenCourseWareWatch clip
“So all aminoacyl-tRNA synthetases require ATP and hydrolyze ATP to AMP and PPI.”— MIT OpenCourseWareWatch clip
“This two-step mechanism is the accepted mechanism for the amino aceyl tRNA synthetases.”— MIT OpenCourseWareWatch clip
“And so we'll look at the mechanism of aminoacyl-tRNA synthetases to see how is the correct amino acid attached, and then what happens if the wrong amino acid is selected.”— MIT OpenCourseWareWatch clip
Practice Speaking “synthetases”
Listen to native pronunciation, record yourself repeating the sentence into your microphone, and receive real-time word-by-word accuracy scoring.
the aminoacyl-tRNA synthetases, which are the enzymes responsible for loading amino acids onto the three prime end of the tRNA.
Hear it in context: “synthetases”
38 clipsThe English word “synthetases”. Phonologically, it consists of 4 syllables (syn · the · ta · ses), with primary lexical stress placed on the 1st (initial) syllable (syn). Grammatically, “synthetases” functions as a noun. SayItVid indexes 38 authentic English video clips demonstrating how native speakers articulate “synthetases” in natural connected speech across American (US: 8 sampled), British (UK), and Australian (AUS) accents, including verified broadcasts from MIT OpenCourseWare.
Spoken Video Transcripts & Contextual Quotes (5 Verified Clips)
- 🇺🇸 USMIT OpenCourseWareClip #1 · @0:42
“today is with a review of tRNAs and then discussing the aminoacyl-tRNA synthetases, which are the enzymes responsible for loading amino acids onto the three prime end of the tRNA. are the enzymes responsible for loading”
- 🇺🇸 USMIT OpenCourseWareClip #2 · @13:42
“are amino acids attached to the tRNA, as shown here? And in order for that to happen, there's a family of enzymes called aminoacyl-tRNA synthetases, or abbreviated aaRS. a family of enzymes called aminoacyl-tRNA synthetases,”
- 🇺🇸 USMIT OpenCourseWareClip #3 · @45:36
“and then the experiment is done to test this. So in the case of these aminoacyl-tRNA synthetases, these ATP PPI exchange assays work well. these ATP PPI exchange assays work well.”
- 🇺🇸 USMIT OpenCourseWareClip #4 · @14:27
“to the mechanism that we see. So all aminoacyl-tRNA synthetases require ATP and hydrolyze ATP to AMP and PPI. require ATP and hydrolyze ATP to AMP and PPI.”
- 🇺🇸 USMIT OpenCourseWareClip #5 · @21:34
“when thinking about reactions. This two-step mechanism is the accepted mechanism for the amino aceyl tRNA synthetases. for the amino aceyl tRNA synthetases.”
Definition & Meaning: “synthetases”
- Any enzyme that catalyzes the synthesis of a biological compound.
- Such an enzyme that, more specifically, uses ATP as a source of energy.
Example Sentences (2)
- “the aminoacyl-tRNA synthetases, which are the enzymes responsible for loading amino acids onto the three prime end of the tRNA.”
- “And in order for that to happen, there's a family of enzymes called aminoacyl-tRNA synthetases, or abbreviated aaRS.”
Common Phrases & Collocations
Pronounce: “synthetases”
- Syllables:
- syn · the · ta · ses
- Primary stress:
- syn
- Hear it in context
- synthetases
Synonyms: “synthetases”
Hear words related in meaning to “synthetases” in real video clips:
Words that Sound Identical (Homophones)
Unique Sound"synthetases" has no true homophones in standard English — there are no other words with identical pronunciation. Unlike sound-alike pairs like there / their or peace / piece, "synthetases" has a completely distinct phonetic identity.
Frequently asked questions about synthetases
How many syllables are in “synthetases”?
“synthetases” has 4 syllables: syn · the · ta · ses.
Where is the stress in “synthetases”?
The primary stress in “synthetases” is on “SYN”. Listen for that stressed syllable in the clips above.
What does “synthetases” mean?
Any enzyme that catalyzes the synthesis of a biological compound.
How can I hear “synthetases” used in real sentences?
This page has 38 real-world video examples of “synthetases” with synchronized subtitles. Use Previous / Next (or ← / → keys) to hear each one at the exact moment it is spoken.
What is the most common pronunciation mistake when saying “synthetases”?
Many learners substitute "th" with "s", "z", "t", or "d". Place the flat blade of your tongue lightly between your upper and lower incisors. Vibrate your vocal cords while pushing air through to produce ⁄ð⁄.