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How to pronounce "prodrug" in English

prodrug is pronounced ˈpɹoʊ.dɹʌɡ, with primary stress on the “PROH” syllable. Hear authentic native speakers pronounce it in 5 clips with synchronized subtitles and timestamps below.

ˈpɹoʊ.dɹʌɡ

PROH·druhg

Primary stress: PROH

Accent:
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IPAˈpɹoʊ.dɹʌɡ
SayPROH-druhg
SyllablesPROH · druhg
Hear it in contextUS
32:24

need to tell you about this AZT, as it's termed, azidothymidine. AZT is what is known in the industry as a prodrug. It's not the actual drug.

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Linguistic Pronunciation Masterclass: “prodrug”

Phonetic mechanics, syllable architecture, and conversational cadence

ˈpɹoʊ.dɹʌɡ

Syllable Architecture & Stress Distribution

Syllable 1Primary Stress

PROH

Gliding diphthong with sustained vocal resonance.

Syllable 2Unstressed

druhg

Reduced vowel sound, relaxed jaw, and minimal vocal effort.

Primary emphasis falls on the first syllable ("PROH"). Raise your pitch and sustain the vowel length on this syllable while relaxing the surrounding syllables.

Common Pronunciation Traps & Learner Mistakes

⚠️ Unstressed Syllable Vowel Reduction (Schwa ⁄ə⁄)

The Trap: Avoid pronouncing every vowel with full acoustic weight. Non-native speakers often over-enunciate unstressed vowels.

How Native Speakers Say It: Only give full vowel clarity to the primary stressed syllable. Relax all unstressed vowels into a neutral, low-energy schwa (⁄ə⁄).

Connected Speech & Natural Conversational Flow

🔗 Consonant-Vowel Linking (Liaison)

When "prodrug" is followed by a word starting with a vowel, glide the final consonant into the opening vowel (e.g. "prodrug is" sounds like "prodrug-iz").

⏱️ Stress-Timed Rhythm

In natural sentences, avoid over-stressing "prodrug" unless it conveys the core contrast or focal point of your message.

Authentic Spoken Quotes from Native Video Context

Verified Transcripts
“AZT is what is known in the industry as a prodrug.”
— MIT OpenCourseWareWatch clip
“Why is it handy to have a prodrug?”
— MIT OpenCourseWareWatch clip
“So prodrug strategies are very useful.”
— MIT OpenCourseWareWatch clip
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IPA:ˈpɹoʊ.dɹʌɡ
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Target Phrase:

AZT is what is known in the industry as a prodrug.

Hear it in context: “prodrug”

5 clips

The English word “prodrug” is transcribed in the International Phonetic Alphabet (IPA) as ˈpɹoʊ.dɹʌɡ (phonetic respelling: PROH-druhg). Phonologically, it consists of 2 syllables (PROH · druhg), with primary lexical stress placed on the 1st (initial) syllable (PROH). Grammatically, “prodrug” functions as a noun, adjective. SayItVid indexes 5 authentic English video clips demonstrating how native speakers articulate “prodrug” in natural connected speech across American (US: 5 sampled), British (UK), and Australian (AUS) accents, including verified broadcasts from MIT OpenCourseWare.

Spoken Video Transcripts & Contextual Quotes (5 Verified Clips)

  • 🇺🇸 USMIT OpenCourseWare
    Clip #1 · @32:24
    “need to tell you about this AZT, as it's termed, azidothymidine. AZT is what is known in the industry as a prodrug. It's not the actual drug.”
  • 🇺🇸 USMIT OpenCourseWare
    Clip #2 · @32:45
    “What has to happen to it to be useful? Why is it handy to have a prodrug? I know there's a lot of questions there,”
  • 🇺🇸 USMIT OpenCourseWare
    Clip #3 · @33:49
    “at 3, which would be the normal place you grow. So prodrug strategies are very useful. It's a way of having drugs that aren't quite drugs yet”
  • 🇺🇸 USMIT OpenCourseWare
    Clip #4 · @32:41
    “It's not the actual drug. Why is it a prodrug? What has to happen to it to be useful?”
  • 🇺🇸 USMIT OpenCourseWare
    Clip #5 · @32:51
    “but they all kind of tie together. So it's a prodrug. It can get into cells, right?”

Definition & Meaning: “prodrug”

NOUN
  • A drug that is administered in an inactive form that is metabolised in the body into a biologically active compound.
ADJECTIVE
  • In favour of recreational drugs.

Example Sentences (3)

  • “In France, the antidrug law forbids all forms of prodrug propaganda.”
  • “AZT is what is known in the industry as a prodrug.”
  • “Why is it handy to have a prodrug?”

Common Phrases & Collocations

prodrug strategieshave a prodrug

Pronounce: “prodrug”

Pronunciation:
PROH-druhg
Syllables:
PROH · druhg
Written Hyphenation:
pro · drug
Primary stress:
PROH
IPA:
ˈpɹoʊ.dɹʌɡ
Hear it in context
prodrug

Words that Rhyme with “prodrug”

-oʊdrʌg
View all 24 rhymes for “prodrug”

Words that Sound Identical (Homophones)

Unique Sound
Explore 800+ homophone pairs

"prodrug" (⁄ˈpɹoʊ.dɹʌɡ⁄) has no true homophones in standard English — there are no other words with identical pronunciation. Unlike sound-alike pairs like there / their or peace / piece, "prodrug" has a completely distinct phonetic identity.

Frequently asked questions about prodrug

How do you pronounce “prodrug”?

“prodrug” is pronounced ⁄ˈpɹoʊ.dɹʌɡ⁄ (PROH-druhg). Listen to the native-speaker clips above to hear it in real conversation.

How many syllables are in “prodrug”?

“prodrug” has 2 syllables: PROH · druhg.

Where is the stress in “prodrug”?

The primary stress in “prodrug” is on “PROH”. Listen for that stressed syllable in the clips above.

What does “prodrug” mean?

A drug that is administered in an inactive form that is metabolised in the body into a biologically active compound.

How can I hear “prodrug” used in real sentences?

This page has 5 real-world video examples of “prodrug” with synchronized subtitles. Use Previous / Next (or ← / → keys) to hear each one at the exact moment it is spoken.

What is the most common pronunciation mistake when saying “prodrug”?

Avoid pronouncing every vowel with full acoustic weight. Non-native speakers often over-enunciate unstressed vowels. Only give full vowel clarity to the primary stressed syllable. Relax all unstressed vowels into a neutral, low-energy schwa (⁄ə⁄).