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How to pronounce "lopinavir" in English

lopinavir is pronounced loʊˈpɪn.əˌvɪɹ, with primary stress on the “PIN” syllable. Hear authentic native speakers pronounce it in 9 clips with synchronized subtitles and timestamps below.

loʊˈpɪn.əˌvɪɹ

loh·PIN·ə·veer

Primary stress: PIN

Accent:
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Hear native speakers say lopinavir in context across real video clips

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IPAloʊˈpɪn.əˌvɪɹ
Sayloh-PIN-ə-veer
Syllablesloh · PIN · ə · veer
Hear it in contextUS
3:49
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Linguistic Pronunciation Masterclass: “lopinavir”

Phonetic mechanics, syllable architecture, and conversational cadence

loʊˈpɪn.əˌvɪɹ

Syllable Architecture & Stress Distribution

Syl. 1Unstressed

loh

Neutral schwa (⁄ə⁄): relaxed jaw, brief unstressed breath.

Syl. 2Primary Stress

PIN

Gliding diphthong with sustained vocal resonance.

Syl. 3Unstressed

ə

Neutral schwa (⁄ə⁄): relaxed jaw, brief unstressed breath.

Syl. 4Unstressed

veer

Neutral schwa (⁄ə⁄): relaxed jaw, brief unstressed breath.

Primary emphasis falls on the second syllable ("PIN"). Raise your pitch and sustain the vowel length on this syllable while relaxing the surrounding syllables.

Common Pronunciation Traps & Learner Mistakes

⚠️ Unstressed Syllable Vowel Reduction (Schwa ⁄ə⁄)

The Trap: Avoid pronouncing every vowel with full acoustic weight. Non-native speakers often over-enunciate unstressed vowels.

How Native Speakers Say It: Only give full vowel clarity to the primary stressed syllable. Relax all unstressed vowels into a neutral, low-energy schwa (⁄ə⁄).

Connected Speech & Natural Conversational Flow

🔗 Consonant-Vowel Linking (Liaison)

When "lopinavir" is followed by a word starting with a vowel, glide the final consonant into the opening vowel (e.g. "lopinavir is" sounds like "lopinavir-iz").

⏱️ Stress-Timed Rhythm

Maintain the stress-timed rhythm of English: compress unstressed syllables rapidly so the beat of "lopinavir" aligns naturally with adjacent words.

Authentic Spoken Quotes from Native Video Context

Verified Transcripts
“More specifically, lopinavir’s role is to block the HIV’s protease enzyme, which interferes with the virus’s replication process.”
— SciShowWatch clip
“The lopinavir-ritonavir combo blocks that enzyme in HIV, which is why they’re classified as HIV protease inhibitors.”
— SciShowWatch clip
“Another part of the WHO megatrial involves a combination of two other antiviral drugs: lopinavir and ritonavir.”
— SciShowWatch clip
“Problem is, when the drug is used on its own, one of our own enzymes breaks down the lopinavir too quickly for it to work, so the ritonavir’s job is to block /that/ enzyme and save us”
— SciShowWatch clip
“Finally, another branch of the megatrial is testing the lopinavir-ritonavir combo plus a protein called interferon-beta.”
— SciShowWatch clip
“And it helps that since lopinavir and ritonavir are already mass-produced for treating HIV, it’s something we could probably roll out very quickly if it turns out to be effective.”
— SciShowWatch clip
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Practice Speaking “lopinavir”

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IPA:loʊˈpɪn.əˌvɪɹ
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More specifically, lopinavir’s role is to block the HIV’s protease enzyme, which interferes with the virus’s replication process.

Hear it in context: “lopinavir”

9 clips

The English word “lopinavir” is transcribed in the International Phonetic Alphabet (IPA) as loʊˈpɪn.əˌvɪɹ (phonetic respelling: loh-PIN-ə-veer). Phonologically, it consists of 4 syllables (loh · PIN · ə · veer), with primary lexical stress placed on the 2nd syllable (PIN). Grammatically, “lopinavir” functions as a noun. SayItVid indexes 9 authentic English video clips demonstrating how native speakers articulate “lopinavir” in natural connected speech across American (US: 8 sampled), British (UK), and Australian (AUS) accents, including verified broadcasts from SciShow.

Spoken Video Transcripts & Contextual Quotes (5 Verified Clips)

  • 🇺🇸 USSciShow
    Clip #1 · @3:49
    “classified as HIV protease inhibitors. More specifically, lopinavir’s role is to block the HIV’s protease enzyme, which interferes with the virus’s replication process. with the virus’s replication process.”
  • 🇺🇸 USSciShow
    Clip #2 · @3:41
    “Proteases are another class of enzyme used by many viruses. The lopinavir-ritonavir combo blocks that enzyme in HIV, which is why they’re classified as HIV protease inhibitors. classified as HIV protease inhibitors.”
  • 🇺🇸 USSciShow
    Clip #3 · @3:27
    “before May. Another part of the WHO megatrial involves a combination of two other antiviral drugs: lopinavir and ritonavir. lopinavir and ritonavir.”
  • 🇺🇸 USSciShow
    Clip #4 · @3:56
    “with the virus’s replication process. Problem is, when the drug is used on its own, one of our own enzymes breaks down the lopinavir too quickly for it to work, so the ritonavir’s job is to block /that/ enzyme and save us too quickly for it to work, so the ritonavir’s job is to block /that/ enzyme and save us”
  • 🇺🇸 USSciShow
    Clip #5 · @5:04
    “it’s something we could probably roll out very quickly if it turns out to be effective. Finally, another branch of the megatrial is testing the lopinavir-ritonavir combo plus a protein called interferon-beta. a protein called interferon-beta.”

Definition & Meaning: “lopinavir”

NOUN
  • An antiretroviral drug C₃₇H₄₈N₄O₅ of the protease inhibitor class that is taken orally usually in conjunction with other retroviral agents (such as ritonavir) to treat HIV infected patients.

Example Sentences (2)

  • “More specifically, lopinavir’s role is to block the HIV’s protease enzyme, which interferes with the virus’s replication process.”
  • “The lopinavir-ritonavir combo blocks that enzyme in HIV, which is why they’re classified as HIV protease inhibitors.”

Common Phrases & Collocations

specifically lopinavircombining lopinavirlopinavir ritonavirritonavir lopinavirdrugs lopinavirsince lopinavir

Pronounce: “lopinavir”

Pronunciation:
loh-PIN-ə-veer
Syllables:
loh · PIN · ə · veer
Written Hyphenation:
lo · pi · na · vir
Primary stress:
PIN
IPA:
loʊˈpɪn.əˌvɪɹ
Hear it in context
lopinavir

Words that Rhyme with “lopinavir”

-ɪnəˌvɪr
View all 2 rhymes for “lopinavir”

Words that Sound Identical (Homophones)

Unique Sound
Explore 800+ homophone pairs

"lopinavir" (⁄loʊˈpɪn.əˌvɪɹ⁄) has no true homophones in standard English — there are no other words with identical pronunciation. Unlike sound-alike pairs like there / their or peace / piece, "lopinavir" has a completely distinct phonetic identity.

Frequently asked questions about lopinavir

How do you pronounce “lopinavir”?

“lopinavir” is pronounced ⁄loʊˈpɪn.əˌvɪɹ⁄ (loh-PIN-ə-veer). Listen to the native-speaker clips above to hear it in real conversation.

How many syllables are in “lopinavir”?

“lopinavir” has 4 syllables: loh · PIN · ə · veer.

Where is the stress in “lopinavir”?

The primary stress in “lopinavir” is on “PIN”. Listen for that stressed syllable in the clips above.

What does “lopinavir” mean?

An antiretroviral drug C₃₇H₄₈N₄O₅ of the protease inhibitor class that is taken orally usually in conjunction with other retroviral agents (such as ritonavir) to treat HIV infected patients.

How can I hear “lopinavir” used in real sentences?

This page has 9 real-world video examples of “lopinavir” with synchronized subtitles. Use Previous / Next (or ← / → keys) to hear each one at the exact moment it is spoken.

What is the most common pronunciation mistake when saying “lopinavir”?

Avoid pronouncing every vowel with full acoustic weight. Non-native speakers often over-enunciate unstressed vowels. Only give full vowel clarity to the primary stressed syllable. Relax all unstressed vowels into a neutral, low-energy schwa (⁄ə⁄).