How to pronounce “ketam” in English

Ketamine is not painting the canvas.

Ketamine treatment lasts a few days and then it wanes.

Ketamine can be addictive.

ketamine is a rapidly acting anti-depressant now some people know

ketamine as a recreational drug of abuse called Special K but we have found that it has potential for the treatment of

ketamine Works quickly and that the response can at least be maintained for

What ketamine is doing, in the painting analogy, is it’s actually able to dial in -- to lift the sort of despair, if you will.

And ketamine allows you to adapt, to change.

So ketamine is a weird one because ketamine has been approved for medical use for decades as an anesthetic.

And ketamine and PCP, they affect the glutamate system in the brain primarily rather than the serotonin system.

So we started studying ketamine and other groups did as well.

After taking ketamine, it didn't make it a party house.

But we're using ketamine to try to understand, again, how do you generate an antidepressant effect?

So now we have ketamine.

There's new ketamine treatment, which is pretty new.

Drugs like ketamine and PCP affect the glutamate system primarily as their first sort of site of action.

say that the ketamine findings are a major advance in the treatment of

depression is that ketamine works very differently than other

in any development of ketamine that leads to formal approval by the FTA and ultimately becomes generally

Now what’s interesting is that ketamine targets glutamate, but it doesn't activate it.

As we continue to study ketamine, there are many different aspects that we're looking at.

And so as we continue to study ketamine, we and other labs, we're trying to understand how can we make this better?

And so now one form of ketamine is actually approved by the FDA in the United States as a treatment for depression.

So there are some advantages over ketamine, and I do get the impression- although I do want the head-to-head comparison research, I'd love to do some of that research-

And you have other drugs such as ketamine and PCP.

minimum it's broken new ground because ketamine Works differently than other anti-depressants and we now know that there are methods to get be people

not work through that mechanism ketamine Works through another neurotransmitter

And some of you may have heard of ketamine.

And for those individuals that were depressed that received ketamine, they had a rapid antidepressant effect -- not within weeks, within hours.

And what we've been able to show is that ketamine, by blocking this fast communication, what it does is it actually strengthens particular connections in the brain,

It's the idea that your brain can adapt and ketamine is able to tap into that.

Some people are looking at when you take ketamine, you have this window of plasticity.

Well, ketamine, as I've told you, is a really remarkable treatment.

But on average, ketamine's antidepressant effects will only last about a week.

And what I mean by that is when ketamine is given, the person is told, "You might feel a little different, but ignore that.

'Yay!' Ketamine. That was not helpful.

they block the re-uptake of the neurotransmitter serotonin ketamine does

that's part of the way uh that ketamine works but researchers now in labs around

the world are probing more deeply about how ketamine can start by working through the glutamate system and then cause other changes in brain function

than the available anti-depressants as I mentioned ketamine is a recreational drug of abuse and we have to be concerned about that

company is studying int you know intranasal forms of ketamine and they

you know to use but I personally feel uh that ketamine is well tolerated in the

CBD line. I did a documentary on ketamine.

And you have other drugs, such as ketamine.

But nonetheless, the drugs like ketamine and PCP, which are in the same class as each other, they initially affect the glutamatergic system in the brain.

will watch for any signs of abuse uh by patients uh probably the way ketamine

What I'm going to talk to you today about is some of our work with ketamine, a really remarkable drug that has rapid antidepressant effects.

But that's why some of the research I’m going to talk to you today about ketamine, which my lab and group has been studying now

And so it sounds pretty remarkable, but it's important to mention up front that ketamine does have risks.