Ketamine, this is the structure of the drug.
Ketamine is not painting the canvas.
Ketamine treatment lasts a few days and then it wanes.
Ketaki Shriram just turned in her dissertation, which is now available in public databases.
What ketamine is doing, in the painting analogy, is it’s actually able to dial in -- to lift the sort of despair, if you will.
And ketamine allows you to adapt, to change.
Jim Ketai, Dan's business partner, and John Varvatos walk in behind them.
that he and Keta allowed the children stay up past their bedtime to see she told him that she wish she could be out
So we started studying ketamine and other groups did as well.
After taking ketamine, it didn't make it a party house.
But we're using ketamine to try to understand, again, how do you generate an antidepressant effect?
So now we have ketamine.
There's new ketamine treatment, which is pretty new.
I knew Jhanvi and Ketaki through film school at Stanford.
And both Jhanvi and Ketaki were former interns, too-- YouTube and Google X. I'd love to hear some words of advice that you might have
Now what’s interesting is that ketamine targets glutamate, but it doesn't activate it.
As we continue to study ketamine, there are many different aspects that we're looking at.
And so as we continue to study ketamine, we and other labs, we're trying to understand how can we make this better?
And some of you may have heard of ketamine.
And for those individuals that were depressed that received ketamine, they had a rapid antidepressant effect -- not within weeks, within hours.
And what we've been able to show is that ketamine, by blocking this fast communication, what it does is it actually strengthens particular connections in the brain,
It's the idea that your brain can adapt and ketamine is able to tap into that.
Some people are looking at when you take ketamine, you have this window of plasticity.
Well, ketamine, as I've told you, is a really remarkable treatment.
CBD line. I did a documentary on ketamine.
What I'm going to talk to you today about is some of our work with ketamine, a really remarkable drug that has rapid antidepressant effects.
But that's why some of the research I’m going to talk to you today about ketamine, which my lab and group has been studying now
And so it sounds pretty remarkable, but it's important to mention up front that ketamine does have risks.
We also have been looking at it from a context of, can we extend ketamine's antidepressant effects?
So one of the things we've been able to do is actually initiate studies to look at giving ketamine, triggering this antidepressant effect
I know we're all really honored and excited to welcome Michael-- to welcome both Jhanvi and Ketaki Shriram, the producers of the film, as well as the director, Kevin
What's been noticed is, in a clinical study that had nothing to do with depression, it was just an observation, they gave a low dose of ketamine.
And the first thing, which we all know, is that ketamine doesn't work on serotonin.
And so, you know, with this diagram, we're showing two nerve cells and just a neurotransmitter in this case ketamine, actually,
And some people describe, with depression, someone noted that, before ketamine treatment, because they didn’t respond to SSRIs,
It's for individuals that don't respond really, that have been most studied in terms of taking ketamine.