How to pronounce“hla2”in English
through steps called positive and negative selection. So in positive selection um they are trained to see um HLA molecules expressed in the thymus.
If the T- cell receptor doesn't bind to HLA molecules the cells die failing positive selection. So importantly all our TCRs are restricted to HLA2.1.
So in our system we have to have HLA A2.1 in the thymus or our cells will fail positive selection. Um subsequently the cells undergo negative selection. If
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