How to pronounce“heterozygotes”in English
I knew that my husband, whose ancestry isn't Eastern European Jewish like mine, had a very low likelihood of also being a carrier for the Tay-Sachs mutation.
While the frequency of heterozygotes, individuals who have one normal copy of the gene and one mutated copy, is about one out of 27 people among Jews of Ashkenazi descent, like me,
in most populations, only one in about 300 people carry the Tay-Sachs mutation.
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