How to pronounce "sirtuins" in English
sir·tu·ins
Hear native speakers say sirtuins in context across real video clips
Linguistic Pronunciation Masterclass: “sirtuins”
Phonetic mechanics, syllable architecture, and conversational cadence
Syllable Architecture & Stress Distribution
sir
Reduced vowel sound, relaxed jaw, and minimal vocal effort.
tu
Reduced vowel sound, relaxed jaw, and minimal vocal effort.
ins
Reduced vowel sound, relaxed jaw, and minimal vocal effort.
Keep the vowel length balanced, placing subtle emphasis on the root morpheme according to standard conversational rhythm.
Common Pronunciation Traps & Learner Mistakes
The Trap: Avoid pronouncing every vowel with full acoustic weight. Non-native speakers often over-enunciate unstressed vowels.
How Native Speakers Say It: Only give full vowel clarity to the primary stressed syllable. Relax all unstressed vowels into a neutral, low-energy schwa (⁄ə⁄).
Connected Speech & Natural Conversational Flow
When "sirtuins" is followed by a word starting with a vowel, glide the final consonant into the opening vowel (e.g. "sirtuins is" sounds like "sirtuins-iz").
Maintain the stress-timed rhythm of English: compress unstressed syllables rapidly so the beat of "sirtuins" aligns naturally with adjacent words.
Authentic Spoken Quotes from Native Video Context
“So the field grew and we and other labs probed what these sirtuins actually do inside of cells.”— TEDx TalksWatch clip
“what we caught we called these genes as the sirtuins okay and we actually have seven of these genes in our body and their names are 31 through 237 and they”— Harvard UniversityWatch clip
“We also talk about David's important discoveries of the sirtuins, particular components that influence what is called the epigenome.”— Andrew HubermanWatch clip
“There are the ones we work on called 'sirtuins' and they control the information in the cell.”— Native SpeakerWatch clip
“These toxins are neurotoxins that suppress these anti-aging proteins called sirtuins.”— Native SpeakerWatch clip
“The NAD+ puts sirtuins to work, preventing cellular information loss.”— NPRWatch clip
Practice Speaking “sirtuins”
Listen to native pronunciation, record yourself repeating the sentence into your microphone, and receive real-time word-by-word accuracy scoring.
So the field grew and we and other labs probed what these sirtuins actually do inside of cells.
Hear it in context: “sirtuins”
42 clipsThe English word “sirtuins”. Phonologically, it consists of 3 syllables (sir · tu · ins). Grammatically, “sirtuins” functions as a noun. SayItVid indexes 42 authentic English video clips demonstrating how native speakers articulate “sirtuins” in natural connected speech across American (US: 8 sampled), British (UK), and Australian (AUS) accents, including verified broadcasts from TEDx Talks, Harvard University, Andrew Huberman.
Spoken Video Transcripts & Contextual Quotes (5 Verified Clips)
- 🇺🇸 USTEDx TalksClip #1 · @5:11
“Evidently the aging field still had some climbing to do. So the field grew and we and other labs probed what these sirtuins actually do inside of cells. and other labs probed what these sirtuins actually do inside of cells.”
- 🇺🇸 USHarvard UniversityClip #2 · @40:47
“set of genes that controls the aging process in these baker's yeast cells and what we caught we called these genes as the sirtuins okay and we actually have seven of these genes in our body and their names are 31 through 237 and they seven of these genes in our body and their names are 31 through 237 and they”
- 🇺🇸 USAndrew HubermanClip #3 · @2:54
“of the biology of aging. We also talk about David's important discoveries of the sirtuins, particular components that influence what is called the epigenome. of the sirtuins, particular components”
- 🇺🇸 USClip #4 · @11:42
“There are three types of longevity gene. There are the ones we work on called 'sirtuins' and they control the information in the cell. In fact, 'sir' in sirtuin stands for 'silent information regulator' number two.”
- 🇺🇸 USClip #5 · @31:25
“glycotoxins, called advanced glycation end products. These toxins are neurotoxins that suppress these anti-aging proteins called sirtuins. these anti-aging proteins called sirtuins.”
Definition & Meaning: “sirtuins”
- Any of several enzymes that act as regulatory factors that mediate the life-extending effects of a low-calorie diet.
Example Sentences (2)
- “So the field grew and we and other labs probed what these sirtuins actually do inside of cells.”
- “what we caught we called these genes as the sirtuins okay and we actually have seven of these genes in our body and their names are 31 through 237 and they”
Common Phrases & Collocations
Pronounce: “sirtuins”
- Syllables:
- sir · tu · ins
- Hear it in context
- sirtuins
Words that Sound Identical (Homophones)
Unique Sound"sirtuins" has no true homophones in standard English — there are no other words with identical pronunciation. Unlike sound-alike pairs like there / their or peace / piece, "sirtuins" has a completely distinct phonetic identity.
Frequently asked questions about sirtuins
How many syllables are in “sirtuins”?
“sirtuins” has 3 syllables: sir · tu · ins.
What does “sirtuins” mean?
Any of several enzymes that act as regulatory factors that mediate the life-extending effects of a low-calorie diet.
How can I hear “sirtuins” used in real sentences?
This page has 42 real-world video examples of “sirtuins” with synchronized subtitles. Use Previous / Next (or ← / → keys) to hear each one at the exact moment it is spoken.
What is the most common pronunciation mistake when saying “sirtuins”?
Avoid pronouncing every vowel with full acoustic weight. Non-native speakers often over-enunciate unstressed vowels. Only give full vowel clarity to the primary stressed syllable. Relax all unstressed vowels into a neutral, low-energy schwa (⁄ə⁄).