How to pronounce“plaques”in English

These plaques are made up of a protein that we came to discover called the beta-amyloid protein.

The plaques are actually when hundreds of thousands, or millions, of these molecules of A beta all get glommed together in this really dense, insoluble blob

amyloid plaques or not.

amyloid plaques is known by the fda not to be a valid clinical indicator it doesn't correlate 27 studies have shown it doesn't

So these plaques are in the gray matter.

develop amyloid plaques in their brain and they get demented.

And then these plaques are forming in our 20s, get worse in our 30s.

That's what female plaques are.

This accumulation of amalloid plaques takes 15 to 20 years and it is not predetermined by your genes.

that accumulation of amalloid plaques, which happens over the course of 15 to 20 years, can be influenced by how we live.

And if enough amyloid plaques accumulate in your brain, at some point it reaches a tipping point that causes neurofibrillary tangles, neuroinflammation,

This accumulation of amyloid plaques takes 15 to 20 years, and can be influenced by how we live.

and look at arterial plaques and let's look at my cholesterol and there's like five to ten studies you would do they

Then we have these superb little plaques showing Scythians riding with their spears.

So there's these characteristic changes of plaques and tangles.

It can withstand a lot of amyloid plaques and a lot of tau tangles before a patient exhibits the first symptom.

They had a lot of plaques left.

It presumably helped to clear amyloid plaques out of the brain, but it was a little bit frustrating that it didn't seem to have any effect on the clinical course

for the collection of more than 700 plaques that mark a life of service.

called tangles and another type outside called plaques.

called tangles-- molecular junk outside neurons called plaques.

its drug agilem reduces amyloid plaques in the brain they did two clinical trials to determine the clinical efficacy

correlate with clinical progression interrupting the amyloid plaques doesn't mean that you're that your alzheimer's

And it looks like there are some kind of plaques.

That is what predisposes you to developing those atherosclerotic plaques.

Separately, surrounding these plaques, and also in other areas of the brain that don't have plaques, there are these other structures called tangles.

He was the first one to describe these plaques and tangles.

And namely, they get plaques and tangles like humans do.

Extracellular junk-- this is stuff like the amyloid that form plaques in Alzheimer's disease.

get drawn into the story by these these plaques and these stories by these animals um so I had the benefit of starting installation about two or three

You go to his office he's got plaques, awards, but that one day went to a pediatric, radiology section and you had young kids afflicted

And so you've gotta have a combination of checks and plaques.

sleep leads to increased buildup of the toxins that lead to the plaques that are found in dementia and Alzheimer's.

And it aggregates inside of neurons, whereas plaques are outside of neurons.

We couldn't get the dose high enough to really clear enough plaques out of people's brains, in order to have that beneficial effect.

the memory score gets worse you see a buildup of these problems or abnormal plaques and Tangles so an older brain is

people who um after death or are diagnoses having Alzheimer's disease and they have plaques and Tangles that appear to be either uh the causes of

cell death or perhaps the residue the aftermath of cell death and these plaques Tangles seem to be uh at the root of certain kinds of um of cognitive

And you walk around Tel Aviv and you see all of the plaques plastered around the streets of the country, of the city,

I mean, there's like plaques on, there's the Pioneer plaques, there's the Voyager 2 Golden Record.

drug development for alzheimer's disease has been the amyloid reducing the amyloid plaques in the brain which correlate with the progression

And here you can see little plaques for each decade.

Je vous parlais tout à l'heure des briques, des plaques, des tubes, des tuiles.

that finally, somebody discovered that the protein that was in these plaques-- because these plaques were just spots on the brain and nobody knew what they were made up

And they saw that there was actually a really tight association between that finding and the degree of amyloid plaques

So this is a technology where you can use a small molecule that binds with high affinity to amyloid plaques.

So their antibody is working-- at least, biochemically-- to remove plaques.

Today I've no fewer than three dozen engraved trophies, plaques, ribbons, plus an entire wall of certificates from the North

I would have been absolutely amazed if people, given these treatments to get rid of plaques, had actually exhibited any significant restoration of cognitive function.