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How to pronounce "phosphodiesters" in English

phosphodiesters is pronounced with standard English phonetics. Hear authentic native speakers pronounce it in 5 clips with synchronized subtitles and timestamps below.

phos·pho·die·sters

Accent:
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Hear native speakers say phosphodiesters in context across real video clips

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Syllablesphos · pho · die · sters
Hear it in contextUS
12:40
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Linguistic Pronunciation Masterclass: “phosphodiesters”

Phonetic mechanics, syllable architecture, and conversational cadence

Syllable Architecture & Stress Distribution

Syl. 1Unstressed

phos

Reduced vowel sound, relaxed jaw, and minimal vocal effort.

Syl. 2Unstressed

pho

Reduced vowel sound, relaxed jaw, and minimal vocal effort.

Syl. 3Unstressed

die

Reduced vowel sound, relaxed jaw, and minimal vocal effort.

Syl. 4Unstressed

sters

Reduced vowel sound, relaxed jaw, and minimal vocal effort.

Keep the vowel length balanced, placing subtle emphasis on the root morpheme according to standard conversational rhythm.

Common Pronunciation Traps & Learner Mistakes

⚠️ Unstressed Syllable Vowel Reduction (Schwa ⁄ə⁄)

The Trap: Avoid pronouncing every vowel with full acoustic weight. Non-native speakers often over-enunciate unstressed vowels.

How Native Speakers Say It: Only give full vowel clarity to the primary stressed syllable. Relax all unstressed vowels into a neutral, low-energy schwa (⁄ə⁄).

Connected Speech & Natural Conversational Flow

🔗 Consonant-Vowel Linking (Liaison)

When "phosphodiesters" is followed by a word starting with a vowel, glide the final consonant into the opening vowel (e.g. "phosphodiesters is" sounds like "phosphodiesters-iz").

⏱️ Stress-Timed Rhythm

Maintain the stress-timed rhythm of English: compress unstressed syllables rapidly so the beat of "phosphodiesters" aligns naturally with adjacent words.

Authentic Spoken Quotes from Native Video Context

Verified Transcripts
“because there's no logic to those names; but really, to remember ribose, deoxyribose, phosphate and phosphodiesters, purines and pyrimidines,”
— MIT OpenCourseWareWatch clip
“and the phosphodiesters to the sugar as well so um this is my professor under”
— TEDx TalksWatch clip
“And in the structure of DNA, you actually have phosphates occurring as phosphodiesters.”
— MIT OpenCourseWareWatch clip
“exterior which are the phospholipids the phosphodiesters which make these negative charges and what we found was you can view your DNA and RNA exactly”
— TEDx TalksWatch clip
“This is actually a bond that is more labile than the PO bonds that we're used to seeing in the phosphodiesters like ATP,”
— MIT OpenCourseWareWatch clip
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Practice Speaking “phosphodiesters”

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Target Phrase:

because there's no logic to those names; but really, to remember ribose, deoxyribose, phosphate and phosphodiesters, purines and pyrimidines,

Hear it in context: “phosphodiesters”

5 clips

The English word “phosphodiesters”. Phonologically, it consists of 4 syllables (phos · pho · die · sters). Grammatically, “phosphodiesters” functions as a noun. SayItVid indexes 5 authentic English video clips demonstrating how native speakers articulate “phosphodiesters” in natural connected speech across American (US: 5 sampled), British (UK), and Australian (AUS) accents, including verified broadcasts from MIT OpenCourseWare, TEDx Talks.

Spoken Video Transcripts & Contextual Quotes (5 Verified Clips)

  • 🇺🇸 USMIT OpenCourseWare
    Clip #1 · @12:40
    “hydrogen-bonding patterns; not to remember fancy names, because there's no logic to those names; but really, to remember ribose, deoxyribose, phosphate and phosphodiesters, purines and pyrimidines, but really, to remember ribose, deoxyribose, phosphate”
  • 🇺🇸 USTEDx Talks
    Clip #2 · @1:17
    “manner with what we call nucleosidic bond connecting the bases to the sugar and the phosphodiesters to the sugar as well so um this is my professor under whom I trained Albertos who started you know asking these kind of questions why”
  • 🇺🇸 USMIT OpenCourseWare
    Clip #3 · @8:44
    “and you commonly have a negative charge on one of those oxygens. And in the structure of DNA, you actually have phosphates occurring as phosphodiesters. have phosphates occurring as phosphodiesters.”
  • 🇺🇸 USTEDx Talks
    Clip #4 · @14:18
    “a hydrophobic interior which is the longchain fatty acids and a hydrophilic exterior which are the phospholipids the phosphodiesters which make these negative charges and what we found was you can view your DNA and RNA exactly negative charges and what we found was you can view your DNA and RNA exactly”
  • 🇺🇸 USMIT OpenCourseWare
    Clip #5 · @19:55
    “a phosphoramidate bond. This is actually a bond that is more labile than the PO bonds that we're used to seeing in the phosphodiesters like ATP, that we're used to seeing in the phosphodiesters like ATP,”

Definition & Meaning: “phosphodiesters”

NOUN
  • any of many biologically active compounds in which two alcohols form ester bonds with phosphate
  • any phospholipid, such as lecithin, that has two ester groups

Example Sentences (2)

  • “because there's no logic to those names; but really, to remember ribose, deoxyribose, phosphate and phosphodiesters, purines and pyrimidines,”
  • “and the phosphodiesters to the sugar as well so um this is my professor under”

Common Phrases & Collocations

phosphodiesters purines

Pronounce: “phosphodiesters”

Syllables:
phos · pho · die · sters
Hear it in context
phosphodiesters

Words that Sound Identical (Homophones)

Unique Sound
Explore 800+ homophone pairs

"phosphodiesters" has no true homophones in standard English — there are no other words with identical pronunciation. Unlike sound-alike pairs like there / their or peace / piece, "phosphodiesters" has a completely distinct phonetic identity.

Frequently asked questions about phosphodiesters

How many syllables are in “phosphodiesters”?

“phosphodiesters” has 4 syllables: phos · pho · die · sters.

What does “phosphodiesters” mean?

any of many biologically active compounds in which two alcohols form ester bonds with phosphate

How can I hear “phosphodiesters” used in real sentences?

This page has 5 real-world video examples of “phosphodiesters” with synchronized subtitles. Use Previous / Next (or ← / → keys) to hear each one at the exact moment it is spoken.

What is the most common pronunciation mistake when saying “phosphodiesters”?

Avoid pronouncing every vowel with full acoustic weight. Non-native speakers often over-enunciate unstressed vowels. Only give full vowel clarity to the primary stressed syllable. Relax all unstressed vowels into a neutral, low-energy schwa (⁄ə⁄).