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How to pronounce "nucleobase" in English

nucleobase is pronounced with standard English phonetics. Hear authentic native speakers pronounce it in 17 clips with synchronized subtitles and timestamps below.

nu·cle·o·base

Accent:
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Hear native speakers say nucleobase in context across real video clips

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Syllablesnu · cle · o · base
Hear it in contextUS
14:01

use ATP as a molecule that has energy that can be unlocked for chemical processes. There's another one of these, which is guanosine triphosphate, where the nucleobase is different. There's another one of these, which

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Linguistic Pronunciation Masterclass: “nucleobase”

Phonetic mechanics, syllable architecture, and conversational cadence

Syllable Architecture & Stress Distribution

Syl. 1Unstressed

nu

Reduced vowel sound, relaxed jaw, and minimal vocal effort.

Syl. 2Unstressed

cle

Reduced vowel sound, relaxed jaw, and minimal vocal effort.

Syl. 3Unstressed

o

Reduced vowel sound, relaxed jaw, and minimal vocal effort.

Syl. 4Unstressed

base

Reduced vowel sound, relaxed jaw, and minimal vocal effort.

Keep the vowel length balanced, placing subtle emphasis on the root morpheme according to standard conversational rhythm.

Common Pronunciation Traps & Learner Mistakes

⚠️ Unstressed Syllable Vowel Reduction (Schwa ⁄ə⁄)

The Trap: Avoid pronouncing every vowel with full acoustic weight. Non-native speakers often over-enunciate unstressed vowels.

How Native Speakers Say It: Only give full vowel clarity to the primary stressed syllable. Relax all unstressed vowels into a neutral, low-energy schwa (⁄ə⁄).

Connected Speech & Natural Conversational Flow

🔗 Consonant-Vowel Linking (Liaison)

When followed by a vowel, insert a subtle glide (/w/ or /j/) to connect into the subsequent word without an abrupt glottal stop.

⏱️ Stress-Timed Rhythm

Maintain the stress-timed rhythm of English: compress unstressed syllables rapidly so the beat of "nucleobase" aligns naturally with adjacent words.

Authentic Spoken Quotes from Native Video Context

Verified Transcripts
“There's another one of these, which is guanosine triphosphate, where the nucleobase is different.”
— MIT OpenCourseWareWatch clip
“So, first of all, what I'm showing here is the nucleobase of the nucleotides.”
— Harvard UniversityWatch clip
“the heat of that discussion and brought himself in a part from PR it is an interest the whole region depends on on keeping the nucleobase very very low”
— Native SpeakerWatch clip
“And the adenine nucleobase can accept and give a pair of hydrogen bonds.”
— MIT OpenCourseWareWatch clip
“In order for the insertion step to be efficient, whenever the nucleobase-- the unnatural nucleotide is in the template or is the incoming triphosphate,”
— Harvard UniversityWatch clip
“So for example, nucleobase, ribose, and in this case,”
— MIT OpenCourseWareWatch clip
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Practice Speaking “nucleobase”

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There's another one of these, which is guanosine triphosphate, where the nucleobase is different.

Hear it in context: “nucleobase”

17 clips

The English word “nucleobase”. Phonologically, it consists of 4 syllables (nu · cle · o · base). Grammatically, “nucleobase” functions as a noun. SayItVid indexes 17 authentic English video clips demonstrating how native speakers articulate “nucleobase” in natural connected speech across American (US: 8 sampled), British (UK), and Australian (AUS) accents, including verified broadcasts from MIT OpenCourseWare, Harvard University.

Spoken Video Transcripts & Contextual Quotes (5 Verified Clips)

  • 🇺🇸 USMIT OpenCourseWare
    Clip #1 · @14:01
    “use ATP as a molecule that has energy that can be unlocked for chemical processes. There's another one of these, which is guanosine triphosphate, where the nucleobase is different. There's another one of these, which”
  • 🇺🇸 USHarvard University
    Clip #2 · @64:13
    “you to absorb in any detail. So, first of all, what I'm showing here is the nucleobase of the nucleotides. is the nucleobase of the nucleotides.”
  • 🇺🇸 US
    Clip #3 · @12:33
    “it that's why the Russians will even poutine phoning in the in the middle of the heat of that discussion and brought himself in a part from PR it is an interest the whole region depends on on keeping the nucleobase very very low interest the whole region depends on on keeping the nucleobase very very low”
  • 🇺🇸 USMIT OpenCourseWare
    Clip #4 · @11:14
    “So that would be a hydrogen bond acceptor. And the adenine nucleobase can accept and give a pair of hydrogen bonds. a pair of hydrogen bonds.”
  • 🇺🇸 USHarvard University
    Clip #5 · @69:13
    “And so it's this position I've noted, there. In order for the insertion step to be efficient, whenever the nucleobase-- the unnatural nucleotide is in the template or is the incoming triphosphate, whenever the nucleobase-- the unnatural nucleotide”

Definition & Meaning: “nucleobase”

NOUN
  • The base of a nucleic acid, such as thymine, uracil, adenine, cytosine and guanine.

Example Sentences (2)

  • “for chemical processes. There's another one of these, which is guanosine triphosphate, where the nucleobase is different.”
  • “So, first of all, what I'm showing here is the nucleobase of the nucleotides.”

Common Phrases & Collocations

unnatural nucleobaseadenine nucleobaseexample nucleobasenucleobase ribose

Pronounce: “nucleobase”

Syllables:
nu · cle · o · base
Hear it in context
nucleobase

Synonyms: “nucleobase”

1 word

Hear words related in meaning to “nucleobase” in real video clips:

Words that Sound Identical (Homophones)

Unique Sound
Explore 800+ homophone pairs

"nucleobase" has no true homophones in standard English — there are no other words with identical pronunciation. Unlike sound-alike pairs like there / their or peace / piece, "nucleobase" has a completely distinct phonetic identity.

Frequently asked questions about nucleobase

How many syllables are in “nucleobase”?

“nucleobase” has 4 syllables: nu · cle · o · base.

What does “nucleobase” mean?

The base of a nucleic acid, such as thymine, uracil, adenine, cytosine and guanine.

How can I hear “nucleobase” used in real sentences?

This page has 17 real-world video examples of “nucleobase” with synchronized subtitles. Use Previous / Next (or ← / → keys) to hear each one at the exact moment it is spoken.

What is the most common pronunciation mistake when saying “nucleobase”?

Avoid pronouncing every vowel with full acoustic weight. Non-native speakers often over-enunciate unstressed vowels. Only give full vowel clarity to the primary stressed syllable. Relax all unstressed vowels into a neutral, low-energy schwa (⁄ə⁄).