How to pronounce "macromolecules" in English
ma·cro·MO·le·cu·les
Primary stress: mo
Hear native speakers say macromolecules in context across real video clips
Linguistic Pronunciation Masterclass: “macromolecules”
Phonetic mechanics, syllable architecture, and conversational cadence
Syllable Architecture & Stress Distribution
ma
Reduced vowel sound, relaxed jaw, and minimal vocal effort.
cro
Reduced vowel sound, relaxed jaw, and minimal vocal effort.
MO
Elevated pitch, sustained vowel length, and full acoustic clarity.
le
Reduced vowel sound, relaxed jaw, and minimal vocal effort.
cu
Reduced vowel sound, relaxed jaw, and minimal vocal effort.
les
Reduced vowel sound, relaxed jaw, and minimal vocal effort.
Primary emphasis falls on the third syllable ("MO"). Raise your pitch and sustain the vowel length on this syllable while relaxing the surrounding syllables.
Common Pronunciation Traps & Learner Mistakes
The Trap: Avoid pronouncing every vowel with full acoustic weight. Non-native speakers often over-enunciate unstressed vowels.
How Native Speakers Say It: Only give full vowel clarity to the primary stressed syllable. Relax all unstressed vowels into a neutral, low-energy schwa (⁄ə⁄).
Connected Speech & Natural Conversational Flow
When "macromolecules" is followed by a word starting with a vowel, glide the final consonant into the opening vowel (e.g. "macromolecules is" sounds like "macromolecules-iz").
Maintain the stress-timed rhythm of English: compress unstressed syllables rapidly so the beat of "macromolecules" aligns naturally with adjacent words.
Authentic Spoken Quotes from Native Video Context
“So those biological macromolecules are made up largely of only six elements-- hydrogen, carbon, nitrogen, and oxygen, phosphorus, and sulfur.”— MIT OpenCourseWareWatch clip
“interact with the different macromolecules, like the DNA or the RNA, you should always remember this is amazing.”— Khan AcademyWatch clip
“Moving on to our macromolecules, which is our cells, the health of our cells.”— Big ThinkWatch clip
“are instances of biological macromolecules such as RNA, DNA, proteins, etc.”— CNBCWatch clip
“Proteins are macromolecules which are composed of amino acids.”— Native SpeakerWatch clip
“Once all of those macromolecules have been dissembled into their monomers, the small intestine’s epithelial cells can finally absorb and transport them through your capillaries”— Native SpeakerWatch clip
Practice Speaking “macromolecules”
Listen to native pronunciation, record yourself repeating the sentence into your microphone, and receive real-time word-by-word accuracy scoring.
So those biological macromolecules are made up largely of only six elements-- hydrogen, carbon, nitrogen, and oxygen, phosphorus, and sulfur.
Hear it in context: “macromolecules”
154 clipsThe English word “macromolecules”. Phonologically, it consists of 6 syllables (ma · cro · mo · le · cu · les), with primary lexical stress placed on the 3rd syllable (mo). Grammatically, “macromolecules” functions as a noun. SayItVid indexes 154 authentic English video clips demonstrating how native speakers articulate “macromolecules” in natural connected speech across American (US: 8 sampled), British (UK), and Australian (AUS) accents, including verified broadcasts from MIT OpenCourseWare, Khan Academy, Big Think.
Spoken Video Transcripts & Contextual Quotes (5 Verified Clips)
- 🇺🇸 USMIT OpenCourseWareClip #1 · @9:14
“of the periodic table. So those biological macromolecules are made up largely of only six elements-- hydrogen, carbon, nitrogen, and oxygen, phosphorus, and sulfur. are made up largely of only six elements--”
- 🇺🇸 USKhan AcademyClip #2 · @6:02
“of how these enzymes interact with the different macromolecules, like the DNA or the RNA, you should always remember this is amazing. like the DNA or the RNA,”
- 🇺🇸 USBig ThinkClip #3 · @7:21
“So it’s easier to get back in shape than it is to get in shape the first time. Moving on to our macromolecules, which is our cells, the health of our cells. how our cells are communicating with one another, how they’re duplicating and so on.”
- 🇺🇸 USCNBCClip #4 · @13:48
“molecules whose exact composition has been designed synthetically, but that ultimately are instances of biological macromolecules such as RNA, DNA, proteins, etc. DNA, proteins, etc.”
- 🇺🇸 USClip #5 · @0:10
“I'm a protein engineer and designer. Proteins are macromolecules which are composed of amino acids. They are made of 20 different types of amino acids.”
Definition & Meaning: “macromolecules”
- A very large molecule, such as a protein, nucleic acid, or synthetic polymer, composed of thousands of covalently bonded atoms.
Example Sentences (3)
- “DNA is a complex macromolecule that carries genetic information.”
- “So those biological macromolecules are made up largely of only six elements-- hydrogen, carbon, nitrogen, and oxygen, phosphorus, and sulfur.”
- “interact with the different macromolecules, like the DNA or the RNA, you should always remember this is amazing.”
Common Phrases & Collocations
Pronounce: “macromolecules”
- Syllables:
- ma · cro · mo · le · cu · les
- Primary stress:
- mo
- Hear it in context
- macromolecules
Words that Sound Identical (Homophones)
Unique Sound"macromolecules" has no true homophones in standard English — there are no other words with identical pronunciation. Unlike sound-alike pairs like there / their or peace / piece, "macromolecules" has a completely distinct phonetic identity.
Frequently asked questions about macromolecules
How many syllables are in “macromolecules”?
“macromolecules” has 6 syllables: ma · cro · mo · le · cu · les.
Where is the stress in “macromolecules”?
The primary stress in “macromolecules” is on “MO”. Listen for that stressed syllable in the clips above.
What does “macromolecules” mean?
A very large molecule, such as a protein, nucleic acid, or synthetic polymer, composed of thousands of covalently bonded atoms.
How can I hear “macromolecules” used in real sentences?
This page has 154 real-world video examples of “macromolecules” with synchronized subtitles. Use Previous / Next (or ← / → keys) to hear each one at the exact moment it is spoken.
What is the most common pronunciation mistake when saying “macromolecules”?
Avoid pronouncing every vowel with full acoustic weight. Non-native speakers often over-enunciate unstressed vowels. Only give full vowel clarity to the primary stressed syllable. Relax all unstressed vowels into a neutral, low-energy schwa (⁄ə⁄).