How to pronounce "ketothiolase" in English
ke·to·thi·o·lase
Hear native speakers say ketothiolase in context across real video clips
Linguistic Pronunciation Masterclass: “ketothiolase”
Phonetic mechanics, syllable architecture, and conversational cadence
Syllable Architecture & Stress Distribution
ke
Reduced vowel sound, relaxed jaw, and minimal vocal effort.
to
Reduced vowel sound, relaxed jaw, and minimal vocal effort.
thi
Reduced vowel sound, relaxed jaw, and minimal vocal effort.
o
Reduced vowel sound, relaxed jaw, and minimal vocal effort.
lase
Reduced vowel sound, relaxed jaw, and minimal vocal effort.
Keep the vowel length balanced, placing subtle emphasis on the root morpheme according to standard conversational rhythm.
Common Pronunciation Traps & Learner Mistakes
The Trap: Many learners substitute "th" with "s", "z", "t", or "d".
How Native Speakers Say It: Place the flat blade of your tongue lightly between your upper and lower incisors. Blow air gently without vocal chord vibration to produce the unvoiced ⁄θ⁄ sound.
The Trap: Pronouncing a hard, aspirated [tʰ] in casual conversation can sound overly formal in North America.
How Native Speakers Say It: In American English, a single "t" between vowels quickly taps against the alveolar ridge like a soft "d" ([ɾ]). In British English, maintain a crisp aspirated [tʰ].
Connected Speech & Natural Conversational Flow
When followed by a vowel, insert a subtle glide (/w/ or /j/) to connect into the subsequent word without an abrupt glottal stop.
Maintain the stress-timed rhythm of English: compress unstressed syllables rapidly so the beat of "ketothiolase" aligns naturally with adjacent words.
Authentic Spoken Quotes from Native Video Context
“going to need another coenzyme A group to come in at this point as part of the beta ketothiolase reaction.”— MIT OpenCourseWareWatch clip
“But because oxaloacetate is limiting, the step at beta ketothiolase backs up, producing a large amount of ketone bodies.”— MIT OpenCourseWareWatch clip
“Remember that beta ketothiolase is the last enzyme that's operative in beta oxidation of fatty acids.”— MIT OpenCourseWareWatch clip
“Then the beta ketothiolase reaction that is the last step in fatty acid bio oxidation reverses owing to the high concentration of product acetyl”— MIT OpenCourseWareWatch clip
“At step four acetyl coenzyme A is converted by beta ketothiolase into two molecules of acetyl coenzyme A. And again, we're”— MIT OpenCourseWareWatch clip
“a thioester in which the residual 14 carbons of the polmitate that we started with are now connected to beta-ketothiolase.”— MIT OpenCourseWareWatch clip
Practice Speaking “ketothiolase”
Listen to native pronunciation, record yourself repeating the sentence into your microphone, and receive real-time word-by-word accuracy scoring.
going to need another coenzyme A group to come in at this point as part of the beta ketothiolase reaction.
Hear it in context: “ketothiolase”
9 clipsThe English word “ketothiolase”. Phonologically, it consists of 5 syllables (ke · to · thi · o · lase). Grammatically, “ketothiolase” functions as a noun. SayItVid indexes 9 authentic English video clips demonstrating how native speakers articulate “ketothiolase” in natural connected speech across American (US: 8 sampled), British (UK), and Australian (AUS) accents, including verified broadcasts from MIT OpenCourseWare.
Spoken Video Transcripts & Contextual Quotes (5 Verified Clips)
- 🇺🇸 USMIT OpenCourseWareClip #1 · @11:21
“of acetyl coenzyme A. And again, we're going to need another coenzyme A group to come in at this point as part of the beta ketothiolase reaction. to come in at this point as part of the beta ketothiolase”
- 🇺🇸 USMIT OpenCourseWareClip #2 · @14:43
“for example, triacylglycerides in order to produce acetyl CoA. But because oxaloacetate is limiting, the step at beta ketothiolase backs up, producing a large amount of ketone bodies. the step at beta ketothiolase backs up,”
- 🇺🇸 USMIT OpenCourseWareClip #3 · @11:28
“reaction. Remember that beta ketothiolase is the last enzyme that's operative in beta oxidation of fatty acids. the last enzyme that's operative in beta oxidation”
- 🇺🇸 USMIT OpenCourseWareClip #4 · @7:20
“The concentration of acetyl CoA starts to accumulate. Then the beta ketothiolase reaction that is the last step in fatty acid bio oxidation reverses owing to the high concentration of product acetyl that is the last step in fatty acid bio oxidation”
- 🇺🇸 USMIT OpenCourseWareClip #5 · @11:11
“This reaction happens in the mitochondrion of the cell. At step four acetyl coenzyme A is converted by beta ketothiolase into two molecules of acetyl coenzyme A. And again, we're converted by beta ketothiolase into two molecules”
Definition & Meaning: “ketothiolase”
- A thiolase that (typically) acts on acetoacetate
Example Sentences (2)
- “going to need another coenzyme A group to come in at this point as part of the beta ketothiolase reaction.”
- “But because oxaloacetate is limiting, the step at beta ketothiolase backs up, producing a large amount of ketone bodies.”
Common Phrases & Collocations
Pronounce: “ketothiolase”
- Syllables:
- ke · to · thi · o · lase
- Hear it in context
- ketothiolase
Words that Sound Identical (Homophones)
Unique Sound"ketothiolase" has no true homophones in standard English — there are no other words with identical pronunciation. Unlike sound-alike pairs like there / their or peace / piece, "ketothiolase" has a completely distinct phonetic identity.
Frequently asked questions about ketothiolase
How many syllables are in “ketothiolase”?
“ketothiolase” has 5 syllables: ke · to · thi · o · lase.
What does “ketothiolase” mean?
A thiolase that (typically) acts on acetoacetate
How can I hear “ketothiolase” used in real sentences?
This page has 9 real-world video examples of “ketothiolase” with synchronized subtitles. Use Previous / Next (or ← / → keys) to hear each one at the exact moment it is spoken.
What is the most common pronunciation mistake when saying “ketothiolase”?
Many learners substitute "th" with "s", "z", "t", or "d". Place the flat blade of your tongue lightly between your upper and lower incisors. Blow air gently without vocal chord vibration to produce the unvoiced ⁄θ⁄ sound.