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How to pronounce "citrulline" in English

citrulline is pronounced with standard English phonetics. Hear authentic native speakers pronounce it in 42 clips with synchronized subtitles and timestamps below.

ci·trul·line

Accent:
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Hear native speakers say citrulline in context across real video clips

1/42
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Syllablesci · trul · line
Hear it in contextUS
1:14:24

this reaction occurs in the mitochondria. And then that citrulline will pick up another nitrogen-- show you how it does this in a minute-- show you how it does this in a minute--

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Linguistic Pronunciation Masterclass: “citrulline”

Phonetic mechanics, syllable architecture, and conversational cadence

Syllable Architecture & Stress Distribution

Syllable 1Unstressed

ci

Reduced vowel sound, relaxed jaw, and minimal vocal effort.

Syllable 2Unstressed

trul

Reduced vowel sound, relaxed jaw, and minimal vocal effort.

Syllable 3Unstressed

line

Reduced vowel sound, relaxed jaw, and minimal vocal effort.

Keep the vowel length balanced, placing subtle emphasis on the root morpheme according to standard conversational rhythm.

Common Pronunciation Traps & Learner Mistakes

⚠️ Unstressed Syllable Vowel Reduction (Schwa ⁄ə⁄)

The Trap: Avoid pronouncing every vowel with full acoustic weight. Non-native speakers often over-enunciate unstressed vowels.

How Native Speakers Say It: Only give full vowel clarity to the primary stressed syllable. Relax all unstressed vowels into a neutral, low-energy schwa (⁄ə⁄).

Connected Speech & Natural Conversational Flow

🔗 Consonant-Vowel Linking (Liaison)

When followed by a vowel, insert a subtle glide (/w/ or /j/) to connect into the subsequent word without an abrupt glottal stop.

⏱️ Stress-Timed Rhythm

Maintain the stress-timed rhythm of English: compress unstressed syllables rapidly so the beat of "citrulline" aligns naturally with adjacent words.

Authentic Spoken Quotes from Native Video Context

Verified Transcripts
“And then that citrulline will pick up another nitrogen-- show you how it does this in a minute--”
— MIT OpenCourseWareWatch clip
“I also just — cautionary note out there, L-citrulline can give people vicious cold sores and canker sores.”
— Andrew HubermanWatch clip
“And so a four-step cycle-- this reaction-- ornithine to citrulline happening in the mitochondria and then regenerating”
— MIT OpenCourseWareWatch clip
“L-citrulline converts to L-arginine, but it lasts much longer in the bloodstream, which is why people tend to use L-citrulline.”
— Andrew HubermanWatch clip
“as well as or anything picking up an ammonia to generate another non-proteinogenic amino acid called citrulline--”
— MIT OpenCourseWareWatch clip
“Andrew Huberman: And what about L-citrulline? I hear about L-citrulline used, it's an over-the-counter supplement, and it's in the arginine pathway.”
— Andrew HubermanWatch clip
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And then that citrulline will pick up another nitrogen-- show you how it does this in a minute--

Hear it in context: “citrulline”

42 clips

The English word “citrulline”. Phonologically, it consists of 3 syllables (ci · trul · line). Grammatically, “citrulline” functions as a noun. SayItVid indexes 42 authentic English video clips demonstrating how native speakers articulate “citrulline” in natural connected speech across American (US: 8 sampled), British (UK), and Australian (AUS) accents, including verified broadcasts from MIT OpenCourseWare, Andrew Huberman.

Spoken Video Transcripts & Contextual Quotes (5 Verified Clips)

  • 🇺🇸 USMIT OpenCourseWare
    Clip #1 · @74:24
    “this reaction occurs in the mitochondria. And then that citrulline will pick up another nitrogen-- show you how it does this in a minute-- show you how it does this in a minute--”
  • 🇺🇸 USAndrew Huberman
    Clip #2 · @52:36
    “but is perhaps not as potent. I also just — cautionary note out there, L-citrulline can give people vicious cold sores and canker sores. sores and canker sores.”
  • 🇺🇸 USMIT OpenCourseWare
    Clip #3 · @74:47
    “be turned back into arginine. And so a four-step cycle-- this reaction-- ornithine to citrulline happening in the mitochondria and then regenerating this reaction-- ornithine to citrulline”
  • 🇺🇸 USAndrew Huberman
    Clip #4 · @53:06
    “So L-arginine is the more direct pathway, but it's very low bioavailability. L-citrulline converts to L-arginine, but it lasts much longer in the bloodstream, which is why people tend to use L-citrulline. Now, you know, in sexual which is why people tend to use L-citrulline. Now, you know, in sexual”
  • 🇺🇸 USMIT OpenCourseWare
    Clip #5 · @74:04
    “But the next reaction, which is ornithine picking up a CO2, as well as or anything picking up an ammonia to generate another non-proteinogenic amino acid called citrulline-- another non-proteinogenic amino acid called citrulline--”

Definition & Meaning: “citrulline”

NOUN
  • An amino acid, first isolated from watermelons, that is an intermediate in the urea cycle.

Example Sentences (2)

  • “And then that citrulline will pick up another nitrogen-- show you how it does this in a minute--”
  • “I also just — cautionary note out there, L-citrulline can give people vicious cold sores and canker sores.”

Pronounce: “citrulline”

Syllables:
ci · trul · line
Hear it in context
citrulline

Words that Sound Identical (Homophones)

Unique Sound
Explore 800+ homophone pairs

"citrulline" has no true homophones in standard English — there are no other words with identical pronunciation. Unlike sound-alike pairs like there / their or peace / piece, "citrulline" has a completely distinct phonetic identity.

Frequently asked questions about citrulline

How many syllables are in “citrulline”?

“citrulline” has 3 syllables: ci · trul · line.

What does “citrulline” mean?

An amino acid, first isolated from watermelons, that is an intermediate in the urea cycle.

How can I hear “citrulline” used in real sentences?

This page has 42 real-world video examples of “citrulline” with synchronized subtitles. Use Previous / Next (or ← / → keys) to hear each one at the exact moment it is spoken.

What is the most common pronunciation mistake when saying “citrulline”?

Avoid pronouncing every vowel with full acoustic weight. Non-native speakers often over-enunciate unstressed vowels. Only give full vowel clarity to the primary stressed syllable. Relax all unstressed vowels into a neutral, low-energy schwa (⁄ə⁄).