How to pronounce“alko”in English
IPA/ælkɒ/
Syllablesal·ko
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3:05
So if we deprotonate an alcohol, we make an alkoxide, the negatively charged conjugate base, which is an excellent nucleophile.
Alkoxides can help us make a different oxygen-containing organic compound: ethers, which have an oxygen connected to two alkyl or aromatic carbons.
Let’s start by looking at a general model of the reaction, which proceeds by an SN2 mechanism.
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