psilocybin project in the early '60s.
Psilocybin mimics it.
Psilocybin , it's really unheard of for someone to be addicted to psilocybin .
with psilocybin and cancer patients or with psilocybin and alcoholics or tobacco addicts-- the depth of the mystical experience
And psilocybin and the other classic psychedelics can latch onto that the same way that serotonin latches onto these brain receptors.
So psilocybin effects serotonin, but then serotonin affects the glutamate system.
like psilocybin , for a therapeutic purpose, the first time in about a half century since the late '60s, so we're really excited about that.
So psilocybin , which people may know is the active agent in so-called magic mushrooms.
So psilocybin , on a lot of dimensions, is just kind of a wonder drug, and everything has its risk, to be clear.
I wasn't ingesting psilocybin that day, just so we're clear.
were giving psilocybin -- this is the ingredient in magic mushrooms.
mushrooms-- extracted psilocybin -- whether that would be promoting of a mystical experience.
whether they've gotten psilocybin or not, which is really remarkable.
what makes the psilocybin treatments a bit more like psychotherapy than traditional psychiatric medications
Does a psilocybin experience help to jumpstart that practice?
Is that because psilocybin is much longer in its antidepressant effects?
My bet is that psilocybin is a superior drug in treating some of these mental health disorders.
what makes the psilocybin treatments, a bit more like psychotherapy than traditional psychiatric medications where you just take the pill and you forget it.
And she had a psilocybin trip.
I had an experience on a guided psilocybin trip where I felt my sense of self scattered to the wind like a blizzard of post-its.
Half of them got the psilocybin , half of them got the placebo as well.
"Mystical experiences occasioned by the hallucinogen psilocybin lead to increases in the personality domain of openness."
So the subjects who got psilocybin experienced profound transformations, as one of them put it "feelings of connectedness with everybody and everything".
The first thing that happens is that psilocybin , once it's circulating through your blood after you've eaten some of it, well, it actually converts
MDMA is not naturally occurring like psilocybin .
The work from our cancer study with psilocybin found that a single high dose of psilocybin reduced depressive symptoms
but my gut tells me that psilocybin is gonna have more profound, longer acting effects than something like ketamine.
So one milligram of pure psilocybin would be a microdose.
The modern research that is taking place with psilocybin here in New York at NYU, at Johns Hopkins, and also at UCLA, has been going on for a while.
And all 10 of the students who took psilocybin had religious experiences and those who took niacin, they first felt a flush, you feel like something is happening, they were really
I'm actually most interested in using something like psilocybin and LSD to treat opioid addiction because compared to ibogaine,
Consistently at the far other end of that continuum are psilocybin mushrooms, ranked as the lowest
It's the exact number of milligrams of psilocybin .
you know, psilocybin checks a lot of those spaces.
- My therapeutic research with psychedelics has primarily used psilocybin , comes in a capsule with a pure compound.
I've done research where we've given one milligram of psilocybin , which is going to be equivalent to what people are shooting for with a so-called microdose.
It's probably gonna be about 10 milligrams of psilocybin .
So although we've adjusted the dose that we deliver of psilocybin by the person's body weight for most of our research, we've recently pulled all the data and figured out,
I'm about to start work on using psilocybin to treat PTSD.
I knew a whole bunch of people who did LSD and psilocybin research back when I was young.
My therapeutic research with psychedelics is primarily used 'psilocybin ,' which is the agent in magic mushrooms.
At the far other end of that continuum are psilocybin mushrooms ranked as the lowest amongst all the major psychoactive compounds
One of the amazing things about the "classic psychedelics," like psilocybin and LSD, is that they're not addictive.
For example, psilocybin , which people may know is the active agent in so-called "magic mushrooms."
So, psilocybin affects serotonin, but then serotonin affects the glutamate system.
So she entered into this trial at NYU and had a high dose psilocybin experience.
And I'm talking about LSD, psilocybin , DMT, mescaline.
in a clinical setting, given them psilocybin , and find that they still have mystical experiences.
That's the fundamental difference between what we're doing in the psilocybin research.
So for example, here we have psilocybin on the left, which comes from magic mushrooms.