And Krebs cycle. Krebs cycle comes up and it seems to be a pretty big pretty big piece of the book.
And the Krebs cycle, it's definitely old.
a complete Krebs cycle as we know it.
They rewire the Krebs cycle.
You get the Krebs cycle.
back to the Krebs cycle, beta oxidation, all that--
His name is Emil Krebs , and he was a German diplomat.
It also affects how the Krebs cycle spins.
And a range of-- there was Emil Krebs .
And both ends of this research have ended up focusing on Krebs cycle.
And they join up in a very weird way because the Krebs cycle is not only about generating energy.
And I was talking about which direction is the Krebs cycle going in.
happen that leads to a shift in direction of the Krebs cycle, it starts going the wrong way around and starts powering growth instead of energy generation,
is driving this reaction between hydrogen and CO2 to make Krebs cycle intermediates.
You want to explain to individuals who aren't familiar with that what the Krebs cycle is?
All of these bacteria going back to the origin of life that are using the Krebs cycle effectively for growth, for biosynthesis, they're bringing in hydrogen.
And when that gums up, then the Krebs cycle kind of slows down and starts to go off in the opposite direction.
- Most of the biology classes then that you take, you learn about the Krebs Cycle and then you have to memorize all the different parts
And that was, of course, the Krebs cycle, this biochemical pathway that we all learn and we all have PTSD about learning and that's it.
And again, a lot we can understand in terms of what's happening with the Krebs cycle because if respiration
he hilariously said this, "We inspired people to become microbrewers," Shipman claimed to Krebs , "because every home brewer who tasted our beer thought
But in the book, I really endeavored to try to go meet living hyperpolyglots because the Krebs is really interesting, and the Mezzofanti character is really interesting.
And that's where the Krebs cycle, the TCA cycle, which breaks down the food that we eat.
And people go through university and the one thing they can remember is how much they hate the Krebs cycle.
But it turns out-- we've known about this since the '60s but a lot of people never heard of it-- is a thing called the reverse Krebs cycle.
And that effectively-- the interesting question is, for the first 2, 3 billion years of life on Earth, the Krebs cycle was basically happening
And we start seeing predators, and prey, and things that almost certainly have a Krebs cycle that's spinning in exactly the opposite direction.
Do you have a kind of a screeching to a halt of this reverse Krebs cycle and it turns and off goes
But that's kind of the framing of it that I have in my mind is there's this turning point, almost literally a turning point where the Krebs cycle screeches to a halt
It turned out around about 2007, 2008, there were several mutations discovered in enzymes in the Krebs cycle that nobody ever
And so it brings it into this same process of burning hydrogen and oxygen, of respiration, the Krebs cycle, and so on, and the fundamental chemistry of life.
The set up is Paul Shipman, the co-founder of what became Redhook, was telling a story to Peter Krebs for his book-- is Krebs right-- "Redhook Beer Pioneer," when