And then what? You, your brothers, your sisters-- your whole family going to start carrying guns now? They're seen as demented or ghetto or gangbangers.
It was beautiful. These mice-- not only did their brains look normal, but they also behaved normally. They did not get demented . And so this was in 1999.
you know, the puppet will be like doing drugs, and we're like is this-- not that any of the Squickerwonkers do drugs. You're writing a demented children's book in the other room.
you know, the puppet will be like doing drugs, and we're like is this-- not that any of the Squickerwonkers do drugs. In terms of other demented children's books, can you recommend some more?
Because you've been there. You know this demented voice that just takes over, right? So my first thing would be to just commit to experiencing the sensation.
And when I heard that, it sounds kind of demented . He has this demented sound. But it seemed to really encapsulate a lot of the themes of the book.
- Even though there's 13 stars. We'll talk about that. - We'll talk about that demented notion of things in just a minute, but only 11 leave. So there are four slaveholding states in the United States: Kentucky, and Missouri, and Maryland, and Delaware remain in the United States. So it's not just North versus South. Those states are all part of the
What happened was even the biggest bones were substantially dissolved. They said that this book is almost dementedly inconsequential.
So you introduce, in mice, those same genetic mutations that humans who have familial forms of Alzheimer's disease have and, lo and behold, these mice develop amyloid plaques in their brain and they get demented . And so what if you administer a vaccine to these mice?
And so this was exciting. They have some other illness that's making them demented , but it's not Alzheimer's disease.
Yeah. There was one quote that's written on the outside of the theater that I love. There's a banner that says that "gloriously demented Christian Borle as Willy Wonka." What did you think about that? Is that a compliment, or-- I mean, obviously.
I think there will be fields where they do that. Vulgar, demented Donald Trump.
And as soon as I'd turn my attention back to my thoughts, guess who was speaking again? Yeah, the demented , insane person would start speaking. And so then I would just pay attention to that, and I would say, OK, what is the wisdom in this?
You're so busy being astonished at how much more smart they are than they were two days ago, at this astonishing rate. And that you could have a similar thing going on with a demented person, watching in awe at one level what is happening. Anyway, he continues chipper, at a book fair in Boston shadowing his antiquarian pal, Eric, he finds a copy of Sir Henry Head's book
And so this was exciting. This is the one that showed a failure in patients who were already demented .
And he wanted to do a similar thing for the deconstruction of the self, a book about dementia. And he said, the subtitle of the book would have been "How to Love a Demented Person." And he would say that, for example, you don't get angry at a six-month-old baby for not talking.
We got this patch. Well, I thought this was a ridiculous, possibly demented idea. Who would do such a crazy thing?
Oh yeah, I do take it as a compliment. That's great. I guess Bugs Bunny is a little bit demented as well, right? Yeah, I guess-- that's a really good comparison, the Bugs Bunny thing, because I was going to bring up later that there's
And I'll squint and I'll look from different angles, and it's inevitably a false alarm. OK, I'm a reliable lecturer here, half demented .
That's his phrase, which is really quite extraordinary. And when I heard that, it sounds kind of demented . He has this demented sound.
This is what Eric's desk looks like at our work. He has taken to making paper dolls, which is demented . But he has taken to making paper dolls of himself.
I did a kayaking course and actually got a certificate that said achieved more swimming than canoeing, kept falling out of it. And swimming, yeah, not great to that either, a lot like a demented turtle. But honestly, sport-- I love sport.
of their genetic syndrome, they will have a 100% chance of getting Alzheimer's disease. So their brain shows the exact same changes as the patient that Alzheimer took care of, and the same changes that all of our older demented patients have. So this genetic evidence is really compelling.
That night, Patricia sat in bed and played with her new Caddy. It was not that different from the standard tablet, except for the guitar-pick shape, and the way that it insisted on asking you demented questions to customize your experience.
Now, those who that eat meat, red meat, white meat, it didn't matter, two to three times more likely to become demented later in life.