cerin via this molecule NAD and that the more active cerin uh then promote better
cerin in a test tube and they also could make cells live longer yeast cells and
cerin okay and we're really really eager to try and figure out what the cerin
cerin and that's led to sort of a a flood of uh uh of Interest I think
I'm Liliana Cerilo. I'm an innovation team at Google called Exploratory.
the activity of cerin and that's led to sort of a a flood of uh uh of Interest I
only are cerin able to do this but we might actually be able to influence their activity uh from outside with drugs and that really is uh I think
molecules are really activating cerin and can protect against diseases of Aging then we should be able to demonstrate that in a mouse so it turns
that activate the cerin they can protect the mouse against diabetes so the mouse will still eat a lot the mouse will still even get fat okay but will stay
activity that cerin might be really be the link between how diet affects how
more active cerin uh then promote better survival and better ability to ward off
molecules are really activating cerin and can protect against diseases of Aging then we should be able to demonstrate that in a mouse so it turns
compounds that activate the cerin they can protect the mouse against diabetes so the mouse will still eat a lot the mouse will still even get fat okay but
the monasteries become the great ceries of text preservation but in fact the Christians are tremendous innovators in
NAD so the activity of cerin which is called deacetylation of other proteins is absolutely under control of NAD no NAD
and these compounds could activate uh cerin in a test tube and they also could
Why am I saying cerulean when I really mean cerise?
there are new kinds of activators now of cerin new chemicals that can activate
tissues that have to be studied so we know what the cerin are doing in each and every tissue so that we know what the effects of a drug are going to be
serans are dead Okay so the NAD links cerin to diet and Metabolism because
remarkable thing uh seem to be that not only are cerin able to do this but we might actually be able to influence their activity
there are new kinds of activators now of cerin new chemicals that can activate
related parts of the brain like the amygdala uh and the locus cerillius. It activates a branch of the nervous system we study called the vagus nerve which is
cin okay and we're really really eager to try and figure out what the cerin
absolutely under control of NAD no NAD cin are dead Okay so the NAD links cerin
cells so we came up with a hypothesis 10 years ago when we discovered this activity that cerin might be really be the link
realistic and will be brought to fruition I think we well you know my lab works on really on cerin and I think there's so
the reason for that at least one of the reasons one of the main reasons is that this low calorie diet activates cerin via this molecule NAD and that the
brought to fruition well I think we well you know my lab works on really on cerin and I
think there's so much to be done so what we know now is just the tip of the iceberg about cerin so first of all there are seven of them in people okay
so to speak have our cake and eat it too and there is a chemical called Resveratrol and a series of genes called cerin which May account for a caloric
tissue by tissue uh and that's going to take a long time so we're deeply involved in that the third thing is Will these cerin