How to pronounce“beta lactam”in English
You don’t want to be hammering together the sides of the Enigma machine with the delicate wiring of the plugboard already in place!
Penicillin was so difficult to isolate because the strained, four-membered beta lactam ring is super sensitive to hydrolysis – it broke open when chemists tried to purify it from the fungus.
So, in our retrosynthesis map, that's the first disconnection and the last bond we’ll make in our synthesis!
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